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February 4, 2020February 4, 2020

PWS Should Be Considered in Differential Diagnosis of Infants in China with Limited Womb Mobility, Low Birth Weight, Study Says

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Prader-Willi syndrome (PWS) should be considered in the differential diagnosis of infants with limited womb mobility, polyhydramnios — excessive accumulation of amniotic fluid — low birth weight and muscle ... Read more

January 30, 2020January 30, 2020

PWS Patients More Prone to Have Blood-clotting Problems Than Other Obese People, Study Shows

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Although uncommon, blood-clotting problems are more likely to occur in people with Prader-Willi syndrome than in obese individuals without the disorder, researchers report. The study, “Age Distribution, Comorbidities and ... Read more

January 28, 2020January 28, 2020

Parents of Children With PWS Feel More Stress in Their Interactions, Study Suggests

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Parents of preschoolers with Prader-Willi Syndrome (PWS) tend to be relatively more stressed and overinvolved in interactions with their children, while the children themselves show less interest and social ... Read more

January 23, 2020January 23, 2020

Adenotonsillectomy May Help Lessen Obstructive Sleep Apnea in PWS Children, Study Suggests

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Adenotonsillectomy — a surgery to remove both the adenoids and tonsils — may help ease obstructive sleep apnea (OSA) in children with Prader-Willi syndrome (PWS), a Taiwanese study suggests. ... Read more

January 21, 2020January 21, 2020

Hip, Knee Replacement Surgery Rare Among PWS Patients, Study Finds

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People with Prader-Willi syndrome (PWS) rarely undergo hip or knee replacement surgery, but those who do tend to be younger than their counterparts in the general population, a large ... Read more

January 16, 2020January 16, 2020

Electrical Nerve Stimulation Eases Temper Outbursts in Adults with PWS, Study Suggests

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Non-invasive vagus nerve stimulation (VNS) — which sends signals to a key nerve that runs through the neck — may help reduce temper outbursts and improve quality of life ... Read more

January 14, 2020January 14, 2020

New Deal Will Fund Development of Tesomet for PWS, Saniona Says

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A new funding deal will aid Saniona‘s development of Tesomet (tesofensine/metoprolol), a potential therapy to help control appetite and weight in people with Prader-Willi syndrome (PWS) and hypothalamic obesity, ... Read more

January 9, 2020January 9, 2020

ZEPHYR Trial Testing Livoletide for Hyperphagia Still Recruiting Children Ages 4-7

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Livoletide, a potential therapy to curb excessive eating among people with Prader-Willi syndrome (PWS), is being tested in a global Phase 2b/3 clinical trial called ZEPHYR. Although recruitment of ... Read more

January 7, 2020January 7, 2020

Phase 3 Trial of DCCR Therapy Candidate for PWS Hits Target Enrollment, Soleno Says

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Target enrollment of approximately 100 participants has been reached in a Phase 3 clinical trial evaluating the investigational oral therapy diazoxide choline controlled-release (DCCR) for reducing excessive appetite in ... Read more

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