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January 21, 2020January 21, 2020

Hip, Knee Replacement Surgery Rare Among PWS Patients, Study Finds

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People with Prader-Willi syndrome (PWS) rarely undergo hip or knee replacement surgery, but those who do tend to be younger than their counterparts in the general population, a large ... Read more

January 16, 2020January 16, 2020

Electrical Nerve Stimulation Eases Temper Outbursts in Adults with PWS, Study Suggests

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Non-invasive vagus nerve stimulation (VNS) — which sends signals to a key nerve that runs through the neck — may help reduce temper outbursts and improve quality of life ... Read more

January 14, 2020January 14, 2020

New Deal Will Fund Development of Tesomet for PWS, Saniona Says

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A new funding deal will aid Saniona‘s development of Tesomet (tesofensine/metoprolol), a potential therapy to help control appetite and weight in people with Prader-Willi syndrome (PWS) and hypothalamic obesity, ... Read more

January 9, 2020January 9, 2020

ZEPHYR Trial Testing Livoletide for Hyperphagia Still Recruiting Children Ages 4-7

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Livoletide, a potential therapy to curb excessive eating among people with Prader-Willi syndrome (PWS), is being tested in a global Phase 2b/3 clinical trial called ZEPHYR. Although recruitment of ... Read more

January 7, 2020January 7, 2020

Phase 3 Trial of DCCR Therapy Candidate for PWS Hits Target Enrollment, Soleno Says

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Target enrollment of approximately 100 participants has been reached in a Phase 3 clinical trial evaluating the investigational oral therapy diazoxide choline controlled-release (DCCR) for reducing excessive appetite in ... Read more

January 6, 2020January 6, 2020

Specific Genetic Subtypes Linked to Distinct Physical Features of PWS, Study Reports

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The specific type of genetic defects in people with Prader-Willi syndrome (PWS) is associated with distinct physical characteristics such as height, weight, and hair thickness, a study has found. ... Read more

January 2, 2020January 2, 2020

Medix Seeks Approval of Tesofensine to Treat Obesity in Mexico

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Medix has submitted a new drug application to the Mexican food and drug administration — Comisión Federal para la Protección contra Riesgos Sanitarios, or COFEPRIS — seeking approval of ... Read more

December 19, 2019December 19, 2019

Poorer Adaptive Ability Tied to Anxiety and Hyperactivity in PWS, Study Says

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Difficulties that people with Prader-Willi syndrome (PWS) have in adapting to their surroundings appear to be linked to psychiatric problems, generalized anxiety and hyperactivity, researchers report. Their study, “The Profiles and ... Read more

December 17, 2019December 17, 2019

Study of Hibernating Animals, PWS Patients Reveals Over 300 Potential Genetic Regulators of Obesity

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A genetic analysis of hibernating animals and people with Prader-Willi syndrome (PWS) has revealed more than 300 small genetic sequences that may regulate fat accumulation and obesity, a study ... Read more

December 10, 2019December 10, 2019

Resistance Training in Young Adults with PWS Possible and Beneficial, Study Suggests

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Despite low muscle tone, young adults with Prader-Willi syndrome can do exercises involving resistance training and likely will benefit from greater muscle strength, a study suggests. The research, “Myokine ... Read more

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