News

Adults With PWS Have Unique Gut Bacteria

Adults with Prader-Willi syndrome (PWS) have a unique gut bacteria composition, characterized by low levels of probiotic species and a high number of other microbes whose potential health and metabolic implications are still unknown, a study has found. The findings indicate that people with PWS may benefit from probiotic…

Mental Rigidity in PWS Goes Beyond Intellectual Disability

Adults with Prader-Willi syndrome (PWS) have greater mental rigidity than those with matching intellectual disability, but without the disease, and those with normal intellectual level, according to a study from France. These findings support the presence of PWS-specific mental flexibility deficits, over and above intellectual problems, the researchers said.

Soleno Looking to Expand Potential Therapies That Work Like DCCR

Soleno Therapeutics has partnered with Vanderbilt University to develop therapies that work as ATP-dependent potassium channel activators for rare diseases, similar to the diazoxide choline controlled release (DCCR) tablets the company thinks might treat Prader-Willi syndrome (PWS). ATP-dependent potassium (or KATP) channels are proteins present in multiple body tissues.