Children with Prader-Willi syndrome (PWS) have high levels of a protein called LIGHT/TNFSF14, which may contribute to obesity and low bone mineral density (BMD), a study suggests. The research, “High levels of LIGHT/TNFSF14 in Prader-Willi syndrome,” was presented at the European Society of Pediatric Endocrinology 2019 meeting in…
Daily consumption of a common probiotic significantly lowered the percentage of abdominal fat, improved insulin resistance, and reduced social withdrawal in patients with Prader-Willi syndrome, a study has found. The research, “Effects of Bifidobacterium animalis subsp. lactis on children with Prader-Willi syndrome: A randomized, double-blind, placebo-controlled, crossover trial,”…
Treatment with growth hormone for eight years led to a lower spine curvature in children with Prader-Willi syndrome (PWS) who developed scoliosis, a preliminary Dutch study reports. The research, “Effects of eight years growth hormone treatment on the onset and progression of scoliosis in children with Prader-Willi syndrome,”…
Supervised exercise sessions at home are an effective strategy to improve the levels of physical activity and walking capacity among women with Prader-Willi syndrome (PWS), a new study suggests. The research, “Increasing physical activity in adult women with Prader–Willi syndrome: A transferability study,” was published in the Journal…
The gut microbiome — the microbial community in the gut — of people with Prader-Willi syndrome (PWS) is more diverse than those of individuals with common obesity, and it may protect them from insulin resistance, a condition that often precedes type 2 diabetes, a study reports. The study, “…
People with Prader-Willi syndrome (PWS) have difficulty recognizing negative emotions throughout their lives, often confusing sadness with anger, a study reports. In addition, they have trouble understanding the sincere intentions of others, the findings also showed. The study, “Profiles and Trajectories of Impaired Social Cognition in People with…
Caregivers of young children with Prader-Willi syndrome (PWS) report low quality of life, highlighting the need for additional support systems for these families, a new Chinese study has found. The findings also indicate that caregivers of PWS children with poor social skills or other symptoms such as obesity or…
Recombinant growth hormones Eutropin and Genotropin were found to produce similar improvements in growth, body fat composition, and motor and cognitive development in infants with Prader-Willi syndrome (PWS), a study has found. The results also suggest that Eutropin is a safe growth hormone to treat infants with PWS.
The birth of children in the U.S. with Prader-Willi syndrome (PWS) — a rare disease caused by deletions in the chromosome 15q11-q13 region of the father — does not follow a seasonal pattern, a study found. The results suggest that seasonal exposure to chromosome-damaging agents…
A grant winner’s research may help to advance a possible treatment of behavioral problems like temper outbursts in Prader-Willi syndrome patients. The treatment, an approved medication but not for PWS, works by modulating the levels of a neurotransmitter that might restore a balance in brain signals. …
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