Telemental health programs, which provide remote mental health services, may be a feasible and effective strategy to address mental health issues that arise for caregivers of children with rare diseases, including Prader-Willi syndrome (PWS), a U.S. study shows. In particular, the researchers noted that individual and group-based programs were…
News
Sleep apnea, or breathing disruptions during sleep, is common in children with Prader-Willi syndrome (PWS) and is more severe than it is in children with sleep apnea but no PWS, according to a study in China. In the PWS group, a higher body mass index (BMI), a…
Aardvark Therapeutics is voluntarily pausing a global clinical trial testing whether its ARD-101 treatment candidate is superior to a placebo at easing hyperphagia, or insatiable hunger, in people with Prader-Willi syndrome (PWS). The company’s decision to pause the Phase 3 HERO trial (NCT06828861) was based on concerning…
Starting growth hormone therapy before 2 years of age does not increase the risk of sleep apnea or breathing disruptions for children with Prader-Willi syndrome (PWS), according to a new study. The findings offer some reassurance for the current medical trend…
Palatin Technologies plans to move two obesity-targeting drugs — experimental therapies designed to activate the melanocortin-4 receptor (MC4R) protein, which is involved in appetite and energy balance — into clinical testing in people with Prader-Willi syndrome (PWS) this year. Planned trials will also test the company’s candidates in…
An ongoing, global clinical trial testing Aardvark Therapeutics’ ARD-101 for hyperphagia, or excessive hunger, in people with Prader-Willi syndrome (PWS) has lowered the minimum enrollment age in the U.S. to allow children as young as 7 to take part, according to a study update. The Phase 3…
Non-obese children with Prader-Willi syndrome (PWS) have imbalances in the blood levels of signaling molecules that facilitate communication between muscles, bones, and fat tissue, a single-center study from Poland suggests. According to the researchers, such imbalances “may impair muscle development and bone metabolism” in “normal-weight children” with the rare…
Adolescents and adults with Prader-Willi syndrome (PWS) in Australia are largely following national healthy eating guidelines, yet they still face high rates of obesity due to consuming significantly more than what’s recommended for the condition. According to a new study, while these patients are choosing the right types of…
Adults with Prader-Willi syndrome (PWS) need substantial support with daily activities, including personal care, social interactions, and problem solving, according to a study from Japan. The results suggest “that once adulthood is reached, daily living skills and adaptive functioning remain largely consistent over time,” the researchers wrote. “Early intervention…
Epigenome editing, a technique that alters the chemical switches that turn genes on or off, can reactivate genes from the mother that are usually silent in Prader-Willi syndrome (PWS), a study using stem cells has found. According to the researchers, these laboratory findings provide new evidence that epigenome editing may…
Recent Posts
- ‘Telemental health’ may help ease stress for caregivers of PWS children
- Severe sleep apnea in PWS children strongly linked to extra weight: Study
- Advocating for your child with Prader-Willi syndrome is a lifelong endeavor
- Collecting pop tabs is a small act that makes a big impact
- Safety concerns over PWS therapy ARD-101 pause global clinical trial
- Starting growth hormone before age 2 does not harm PWS sleep
- I’m hopeful a new treatment will benefit my son with Prader-Willi syndrome
- Palatin to test 2 obesity-targeting drugs for PWS in clinical trials this year
- Still-recruiting ARD-101 trial for PWS lowers US enrollment age to 7
- For rare disease families, February is a month of both love and awareness