Alberto Molano, PhD,  —

Neonatal hypotonia (low muscle tone), reduced fetal movement, feeding difficulties, and cryptorchidism (undescended testes) should immediately suggest a diagnosis of Prader-Willi syndrome (PWS), according to a recent study. “Neonatal Features of the Prader-Willi Syndrome; The Case for Making the Diagnosis During the First Week of Life,” was published in…

Saniona announced it has completed the second part of its exploratory Phase 2a study testing Tesomet (tesofensine/metoprolol) as a therapy for Prader-Willi syndrome, involving nine adolescent patients treated for three months. The treatment seemed to be well-tolerated, and eight of the nine participants agreed to continue in a 24-week open…