Author Archives: Margarida Azevedo

PWS-associated Gene Involved in Integration of Vision and Motor Control in the Brain

Altered gene expression underlies impaired function of brain areas regulating vision and motor control, which may be associated with behavioral issues in people with Prader-Willi syndrome (PWS) and other disorders, a study suggests. The study, “Central neurogenetic signatures of the visuomotor integration system,” was published…

Lipidio Completes First Financing Step to Develop PWS Therapy GDD3898

Lipidio Pharmaceuticals has completed the first step of financing to support its development of GDD3898, a treatment candidate for Prader Willi syndrome (PWS) and other conditions associated with obesity. Investors in this series A funding include the Foundation for Prader Willi Research. “Prader-Willi syndrome, or PWS,…

Phase 2 Trial Launched to Test Pitolisant for Excessive Sleepiness in PWS

Harmony Biosciences has kicked off a Phase 2 clinical trial to evaluate the safety and effectiveness of pitolisant to treat excessive daytime sleepiness in people with Prader-Willi syndrome, ages 6 to 65. The study (NCT04257929) is expected to start enrolling participants soon, the company said in a…