News

Soleno Therapeutics and the U.S. Food and Drug Administration recently held a meeting to mark the end of a successful Phase 2 clinical trial evaluating diazoxide choline controlled-release (DCCR) for the treatment of Prader-Willi syndrome (PWS). DCCR is an extended-release, crystalline salt formulation of diazoxide designed to…

Long-term use of growth hormone therapy in young adults with Prader-Willi syndrome (PWS) fails to prevent bone deterioration. But a combination of growth hormone therapy and sex hormone therapy may have therapeutic potential for PWS patients, a new study suggests. The findings were reported in a study titled, “…

In people with Prader-Willi syndrome, the severity of aberrant behaviors declines with age, a phenomenon that starts at around age 30, according to Japanese researchers. Food-related behaviors, however, are maintained and don’t seem to change as patients grow older. The study, “Aberrant, autistic, and food-related behaviors…

Saniona recently reported encouraging results from its exploratory Phase 2a clinical trial evaluating Tesomet (tesofensine/metoprolol) in patients with Prader-Willi syndrome (PWS). PWS is a genetic disorder that begins in childhood. People with Prader-Willi syndrome always feel hungry, which can often lead to obesity and type 2…

A team of researchers was able to restore the normal level of genes that are usually silenced in Prader-Willi syndrome (PWS) in patient neurons grown in the lab. The study, led by researchers at the University of Connecticut, is titled “Zinc finger protein 274 regulates imprinted expression…