Having predictable rules and routines around food is not only a useful management tool for people with Prader-Willi syndrome (PWS) but also absolutely central to managing hyperphagia, a hallmark symptom of the disease characterized by uncontrollable hunger…
News
The U.S. Food and Drug Administration (FDA) has lifted the hold on late-stage clinical testing of ARD-101, an investigational oral therapy for people with Prader-Willi syndrome (PWS) and hyperphagia, an insatiable feeling of hunger. “We are pleased that the FDA has lifted the clinical hold on ARD-101, allowing…
An international survey found that clinicians with the most experience caring for infants with Prader-Willi syndrome (PWS) are more likely to forgo a sleep study before starting growth hormone therapy — contrary to current guidelines. For U.S. doctors, the most commonly cited reason was avoiding a delay in…
Testosterone replacement therapy (TRT) may help preserve bone health and improve body composition in boys and young men with Prader-Willi syndrome (PWS), without worsening challenging behaviors in most cases, according to a study in the Netherlands. Although TRT has raised concerns about worsening behavioral problems in males with PWS, more…
A structured interdisciplinary inpatient program for adolescents and young adults with Prader-Willi syndrome (PWS) and severe behavioral problems was associated with behavioral, functional, and metabolic improvements, a small study found. The study included nine participants who underwent an inpatient program combining behavioral therapy, supervised nutrition, rehabilitation, and psychiatric care.
Palatin Technologies expects to begin early-stage clinical trials next year for two experimental treatments designed to curb extreme hunger in people with Prader-Willi syndrome (PWS) and other rare obesity conditions. While Palatin previously anticipated launching these Phase 1 trials this year, the company has pushed the start…
The duration of low blood oxygen levels during sleep may vary among people with Prader-Willi syndrome (PWS) depending on their genetic subtype, a small study in Brazil suggests. Researchers found that children and young adults with PWS caused by a genetic deletion — the most common PWS cause —…
Nearly 400 civic, business, and philanthropic leaders in South Florida gathered this week for a second annual event aimed at raising funds to support people with Prader-Willi syndrome (PWS) and other developmental disorders, particularly as they “transition into adulthood.” The fundraising gala was hosted by the Supreme Twins…
Five years of growth hormone (GH) treatment allows children with Prader-Willi syndrome (PWS) who are experiencing failure to thrive at the start of treatment to develop similar height-adjusted lean body mass, or non-fat tissue, to those without failure to thrive at GH initiation. That’s according to a study in…
Starting growth hormone therapy as early as possible may help children with Prader-Willi syndrome (PWS) develop stronger thinking and language skills, according to a study from Taiwan. “In addition to improved motor development, on the basis of previous studies, our study demonstrated that [growth hormone therapy] initiation at 3…
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